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When does a fetus develop a brain?

Your baby's brain begins developing early in pregnancy, just three weeks after fertilization, and continues throughout your pregnancy. The third trimester is when major developments happen, and your baby's brain triples in weight. Taking folic acid and eating a well-balanced diet that includes fish rich in omega-3s can help support your baby's brain development during pregnancy and beyond.

illustration of a fetal brain development
Photo credit: Jonathan Dimes for BabyCenter

It's probably no surprise that your baby's brain is one of the first major organs to start developing. But you may not know that it will continue to grow until your child is in their early 20s!

Together, the brain and spinal cord make up the central nervous system. The brain is enclosed within the skull, and the spinal cord is encased within a flexible spinal column made up of 33 separate bones (vertebrae). A network of nerves branches off the spinal cord, and these nerves send signals to and receive information from various organs.

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Early fetal brain development

The first part develops just three weeks after fertilization as an oval-shaped disk of tissue called the neural plate. This early (5 weeks pregnant), your baby is an embryo that looks like a tiny tadpole, with the neural plate running down the middle from head to tail.

Over the course of this week, the edges of the plate rise and fold toward each other, forming the neural tube that will become your baby's spine and brain. At this point, the ends of the tube remain open, and the brain starts to take shape at the top of the tube. Near the bottom is the structure that will eventually become the tailbone.

By the time you're 6 weeks pregnant, the neural tube is completely closed at both ends, and at the top of the tube, the brain consists of three areas:

  • The forebrain develops into the cerebrum, which controls certain brain functions , like thinking and problem-solving.
  • The midbrain is involved in processing visual and auditory information.
  • The hindbrain develops into the cerebellum, which manages balance and coordination, as well as the medulla, which is the control center for the body's automatic activities, like blood pressure and heart rate.

How the nervous system develops

Located along the edges of the developing neural tube is the neural crest. This crest, along with the brain and spinal cord, give rise to the millions of nerves that branch out all over the body.

From 8 weeks of pregnancy on, these nerves are making connections not only with each other, but also with muscles and other tissues as well as organs, like the eyes and ears. At 12 weeks, the nerves start sending out simple signals that cause reflex behaviors. For example, your baby's fingers can open and close, and their toes can curl. Your baby can also squint their eye muscles and make sucking movements with their mouth.

By about 28 weeks, nerves connect with their designated organs so your baby's senses of hearing, smell, and taste can begin to function. Some nerve cells develop a sheath of insulating material called myelin that speeds up signaling between nerves. Myelin starts to form in the third trimester and continues after birth and well into adulthood.

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Although brain development takes place throughout pregnancy, it really kicks into high gear in the last trimester as the brain triples in weight. During these final weeks, the cerebrum also develops deep grooves that provide extra surface area without taking up more room in the skull. This wrinkly outer layer is known as the cerebral cortex.

Your baby's brain at birth

How well does your baby's brain function at birth? Your newborn arrives equipped with all kinds of fascinating abilities that reflect the amazing growth from tiny neural plate to full-fledged nervous system:

  • They'll have a wide range of reflexes that you can test yourself. For example, if you stroke your baby's cheek, they'll turn their head toward you (rooting reflex). Put your finger in their mouth, and they'll automatically begin to suck (sucking reflex). When you hold your baby upright with feet touching the floor, they'll make little stepping movements (stepping reflex).
  • Your baby can recognize your voice! Starting around the third trimester, your little one can eavesdrop on your conversations, and by the time they're born, they'll show a clear preference for your voice over others. Your little one will even turn their head when they hear you.
  • Although you might imagine that your baby would be just as interested in looking at a toy or the TV, research shows that babies are especially attuned to human faces, preferring them to random designs.

And keep in mind that because your baby's brain continues to grow after birth, every day new neural connections form between the different parts of the brain, adding to your child's growing store of knowledge, memory, and experience. Find out how you can help raise a smart baby

What you can do to support fetal brain development

  • Take a folic acid supplement during (and even before) pregnancy. Folic acid is a B vitamin that's crucial to the development of the brain and spinal cord. Getting enough folic acid lowers the risk of neural tube defects like spina bifida and anencephaly. The neural tube develops very early (even before many women even know they're pregnant), so experts recommend that you take 400 micrograms of folic acid daily at least a month before you start trying to get pregnant. You can get it from certain prenatal vitamins or you can take it as a separate supplement.
  • Eat cooked fish 2 to 3 times a week. Fish – especially fatty fish like salmon – contains omega-3 fatty acids, which research suggests boosts your baby's brain development during pregnancy and into childhood. See our article on how to choose fish that's rich in omega-3's but low in mercury and other contaminants, which can harm a baby's developing nervous system.
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Key milestones in fetal brain development

Weeks pregnantMilestone
5 weeksThe neural plate forms.
6 weeksThe neural tube forms and closes. The brain is now made up of three areas (forebrain, midbrain, and hindbrain), and the ventricles have formed.
8 weeksA network of nerves starts to extend throughout the body.
12 weeksFetal reflexes are present.
28 weeksSenses of hearing, smell, and touch are developed and functional.
28 to 39 weeksThe brain triples in weight, and deep grooves develop in the cerebrum to allow more surface area for brain neurons. Myelin starts to develop along some neural pathways.

Learn more:

Follow your baby's amazing development
Sources

BabyCenter's editorial team is committed to providing the most helpful and trustworthy pregnancy and parenting information in the world. When creating and updating content, we rely on credible sources: respected health organizations, professional groups of doctors and other experts, and published studies in peer-reviewed journals. We believe you should always know the source of the information you're seeing. Learn more about our editorial and medical review policies.

CDC. 2018. Folic acid. U.S. Centers for Disease Control and Prevention. https://www.cdc.gov/ncbddd/folicacid/recommendations.htmlOpens a new window [Accessed December 2021]

FDA. 2018. Eating fish: What pregnant women and parents should know. U.S. Food and Drug Administration. https://www.fda.gov/food/consumers/advice-about-eating-fishOpens a new window [Accessed December 2021]

Moore KL, Persaud TVN, and Torchia MG. 2016. Before We Are Born: Essentials of Embryology and Birth Defects. 9th ed. Philadelphia, PA: Elsevier. [Accessed December 2021]

NIH. 2016. The teen brain: 6 things to know. National Institute of Mental Health. https://www.nimh.nih.gov/health/publications/the-teen-brain-7-things-to-knowOpens a new window [Accessed December 2021]

Qiu A et al. 2015. Diffusion tensor imaging for understanding brain development in early life. Annual Review of Psychology 66:853-876. https://www.annualreviews.org/doi/10.1146/annurev-psych-010814-015340Opens a new window [Accessed December 2021]

Sadler TW. 2015. Langman's Medical Embryology. 14th ed. Philadelphia, PA: Lippincott, Williams & Wilkins. [Accessed December 2021]

Kathleen Scogna is the senior director of education at the Society for Maternal-Fetal Medicine and a former freelance medical writer based in Baltimore.
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